Shahrazad S Al Jobori1*
Every year, thousands of patients of all ages are in desperate need of bone marrow transplants which may be their only chance to survive. Some patients with aplastic anemia, leukemia, lymphoma or other cancers are lucky to have a family member who is genetically matched. However, about 70% of patients have no matched relatives. Their lives depend on finding an unrelated donor, who has a compatible tissue typing. The relevance of such a project arises from the fact the markers, Human Leukocyte Antigen system used in matching are inherited, patients are more likely to match someone from their own race or ethnicity. WHO report released for 2014 regarding cancer registry in Iraq shows that Leukemia is the second leading cause of death among females & the third leading cause of the death among males, lymphoma and multiple myeloma are the second leading cause of death among males and the third leading cause of death among females. The registry can reside in Baghdad, the capital of Iraq or another big Province to facilitate donor registration and Human Leukocyte antigen examination supported by mass media campaigns especially focused on patients relatives, friends as well as medical and paramedical personnel. Recourses including expertise in the field of genetics is required as well as laboratory facilities for HLA typing, computer programming skills for data management, financial allocations needed and on the top of all it needs a political will and commitment for its adoption. Such a national registry would help patients in need for allogeneic bone marrow transplantation (BMT) and would be the starting point towards improving bone marrow transplantation in Iraq. As well as this registry can be connected to the registries around the world to allow for a more fruitful search for the patients giving them the chance of recovery and since BMT center in Iraq is only performing autologous BMT for leukemic patients, the Ministry of Health at the time being can coordinate with Iran for example to send the eligible patients for BMT. INBMR is an important project that would aid patients in need for BMT find a suitable unrelated donor, a problem found in 70% of patients.
Keywords: Bone marrow transplant, HLA typing, Ministry of Health, INBMR
- Asian American Donor Program. [Website]
- Ali HA. Outcome of unrelated HSCT in patients lacking HLA matched related donors: Iranian stem cell donor program. Congress of APBMT, Hangzhou, China
- Petersdorf EW. The World Marrow Donor Association: 20 years of international collaboration for the support of unrelated donor and cord blood hematopoietic cell transplantation. Bone Marrow Transplantation 2010;45:807-810. [PubMed]
- Hurley CK, Foeken L, Horowitz M.Standards, regulations and accreditation for registries involved in the worldwide exchange of hematopoietic stem cell donors and products. Bone Marrow Transplantation 2010;45:819-824. [PubMed]
- World Marrow Donor Association, International Standardsfor Unrelated Hematopoietic Progenitor Cell Donor Registries, Approval date 05/04/2013. [PDF, version]
- Bone marrow donation in media. [Website]
- World health organization official website (bone marrow transplant). [Website]
- World health organization, regional office for the eastern Mediterranean region, Report on the regional meeting on haemoglobinopathies and genetic diseases in the Eastern Mediterranean Region,Amman, Jordan 27–30 June 2011.
- Gan GG, The A, Chan LL, Cheong SK, Chang KM, Ibrahim HM. Bone marrow and stem cell transplantation: Malaysian experience. Bone Marrow Transplantation 2008;42:S103-S105. [Abstract/Full-Text]
- Victoria A. Butterworth, Roberta G. et al. Psychosocial effects of unrelated bone marrow donation: experiences of the national marrow donor program. Blood 1993;81(7):1947-1959. [Abstract/Full-Text]
READ THE FULL ARTICLE
1. Access this article through Open Athens
2. Access this article through your login credentials or your institution
3. Purchase this article at rate $55.00 and received Full-Text/PDF
You will have online immediate access to article following the completion of this purchase and you may download and print a copy of each article for your personal use. Use the coding below to purchase your article as PDF by credit card, debit card, PayPal will be asked to supply your billing card information. Before continue with your purchase please read carefully BM–Publisher terms and conditions of purchase.
For any technique error please contact us and will be a response to sending purchase article by email.
Thank you for visiting Journal of Cellular Cancer. * = Required fields