Tag: Notch1

Co-activation of Notch and Wnt mediates progression of ovarian cancer cells

 Minoru B.Tada¹, Suzan Kamath, Lindsell E. Norton, Kathleen B. Loomes∗AbstractOvarian cancer is the most lethal gynecologic malignancy. In recent data have shown constitutive upregulation of the Notch1 signaling pathway in many forms of solid and hematological malignancies. However, it remains unclear whether this signaling pathway is activated in ovarian cancer cells. In the present study, […]