Tag: Ovarian cancer

Co-activation of Notch and Wnt mediates progression of ovarian cancer cells

 Minoru B.Tada¹, Suzan Kamath, Lindsell E. Norton, Kathleen B. Loomes∗AbstractOvarian cancer is the most lethal gynecologic malignancy. In recent data have shown constitutive upregulation of the Notch1 signaling pathway in many forms of solid and hematological malignancies. However, it remains unclear whether this signaling pathway is activated in ovarian cancer cells. In the present study, […]

Critical role of TGF-β1-induced peritoneal metastasis of ovarian cancer cell through up-regulation of TGF-β type I receptor

http://dx.doi.org/10.18081/jcc/016-06/24-27 Journal of Cellular Cancer Volume 8, Issue 1, pages 24-27 Received January 21, 2016; accepted May 26, 2016; published June 19, 2016  Rory A. Collins, Andres D. Metspalu, Carla M. van El, Andersen S. Mamsen, Charles Y. Dondorp, Lidewij E. Henneman¹*    Abstract Ovarian cancer is the most lethal gynecologic malignancy in female due to […]