Journal of Cellular Cancer

ISSN 2475-2037 (Online)

Menu
  • Home
  • About Journal
    • Aims and Scope
    • Time Lines
    • Copyright
    • Publication Ethics
    • Permanency of Content
    • Statement of informed consent
    • Subscription
    • Terms and conditions of purchase
  • Editors
  • Guides
    • Guide for Authors
    • Guidance for Peer Reviewers
    • Article processing charges
    • Protection of Human Subjects and Animals
    • Conflict of Interest
    • Publishing Process
    • Registration of Trials
  • Submit Manuscript
  • Current Issue
  • Archive
  • Contact Us
Menu

Role of exercise on metabolism of breast cancer

Posted on June 4, 2012September 16, 2016 by bm-jcc

crossMark

Journal of Cellular Cancer  Volume 4, Issue 1, pages 1-8 June 2012


Sébastien Witkowsk, David Rebollo, Luís McAuliffe

Abstract

Physical activity intersects with oncology in both the pre-diagnosis and survivorship settings. Obesity and sedentary lifestyle are associated with a higher risk of breast cancer recurrence and onset of comorbid conditions in women diagnosed with breast cancer. Participants were 88 premenopausal and 150 postmenopausal breast cancer survivors who were enrolled in this study. At baseline and 8 months, participants completed an interview-administered physical activity questionnaire, which was used to assess the past 8 months of recreational activity.Taken together, current evidence suggests that exercise may have beneficial effects on breast cancer prevention and outcome.

Keywords: Breast cancer; Exercise; Obesity; Physical activity

Purchase access to this articleReferencesExport Citation
Purchase this article at rate $55.00 and received Full-Text/PDF You will have online immediate access to article following the completion of this purchase and you may download and print a copy of each article for your personal use. Purchase Article

References

  1. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003;348:1625–1638. [PubMed] [Cross Ref]
  2. Seewaldt VL, Goldenberg V, Jones LW, et al. Overweight and obese perimenopausal and postmenopausal women exhibit increased abnormal mammary epithelial cytology. Cancer Epidemiol Biomarkers Prev 2007;16:613–616. [PubMed] [Cross Ref]
  3. Berclaz G, Li S, Price KN, et al. Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience. Ann Oncol 2004;15:875–884. [PubMed] [Cross Ref]
  4. Gesta S, Tseng YH, Kahn CR. Developmental origin of fat: tracking obesity to its source. Cell 2007;131:242–256. [PubMed] [Cross Ref]
  5. Bruce KD, Cagampang FR. Epigenetic priming of the metabolic syndrome. Toxicol Mechanisms Methods 2011;21:353–361. [PubMed] [Cross Ref]
  6. Mantzoros C, Petridou E, Dessypris N, et al. Adiponectin and breast cancer risk. J Clin Endocrinol Metab 2004;89:1102–1107. [PubMed] [Cross Ref]
  7. Bodmer M, Meier C, Krahenbuhl S, et al. Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 2010;33:1304–1308. [PubMed] [Cross Ref]
  8. Vazquez-Martin A, Oliveras-Ferraros C, Barco S, et al. The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells. Breast Cancer Res Treat 2011;126:355–364. [PubMed]
  9. National Center for Chronic Disease Prevention and Health Promotion and Centers for Disease Control and Prevention (1996). Physical Activity and Health: A Report of the Surgeon General. Retrieved June 26, 2009, from: http://www.cdc.gov/nccdphp/sgr/sgr.htm.
  10. Slattery, ML. Physical activity and colorectal cancer. Sports Medicine 2004; 34(4): 239–252.
  11. IARC Handbooks of Cancer Prevention. Weight Control and Physical Activity. Vol. 6. 2002.
  12. Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 2009;69:7507–7516. [PubMed]
  13. Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care 2006;29:254–258. [PubMed]
  14. Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH. Home-based physical activity intervention for breast cancer patients. Journal of Clinical Oncology 2005; 23(15): 3577–3587. [PubMed]
  15. McTiernan A, editor. Cancer Prevention and Management Through Exercise and Weight Control. Boca Raton: Taylor & Francis Group, LLC, 2006.
  16. Meyerhardt JA, Giovannucci EL, Holmes MD, et al. Physical activity and survival after colorectal cancer diagnosis. Journal of Clinical Oncology 2006; 24(22):3527–3534.
  17. Loescher LJ, Welch-McCaffrey D, Leigh SA, et al: Surviving adult cancers. Part 1: Physiologic effects. Ann Intern Med 1989;111:411-432.
  18. aghian AG, Assaad SI, Niemierko A, et al: Risk of pneumonitis in breast cancer patients treated with radiation therapy and combination chemotherapy with paclitaxel. J Natl Cancer Inst 2001;93:1806 -1811.
  19. US Department of Health and Human Services: Physical Activity and Health: A Report of the Surgeon General. Atlanta, GA, US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Promotion, US Government Printing Office,1996.
  20. Segal R, Evans W, Johnson D, et al. Structured exercise improves physical functioning in women with stages I and II breast cancer: Results of a randomized controlled trial. J Clin Oncol 2001;19:657-665. [Abstract/Full-Text]
  21. Dimeo FC, Tilmann MH, Bertz H, et al. Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation. Cancer 1997;79:1717-1722.

Journal of cellular cancer picture

 

 

 

 

 

 

Sébastien Witkowsk, David Rebollo, Luís McAuliffe. Role of exercise on metabolism of breast cancer Cancer 2012; 4(1):1-8.

Bibliographic Details

Bibliographic Details
Journal of Cellular Cancer
Journal Abbreviation: JCC
DOI: 10.18081/jcc.date.pages

ISSN 2475-2037
Manuscript Service: jcc.manuscript@bm-jcc.net

Archives

2024© Journal Management System. BM