Research Article Journal of Cellular Cancer Volume 7, Issue 1, pages 43-56 Published: June 22, 2015 Mark Fullerton, Lihua Li, Ling Wu, David B. Mulier, Xian Chen, Celeste B. Determan, Jean Friese, Ling Yao Abstract Most ovarian cancers are highly invasive and the high burden of metastatic disease make them a leading cause of mortality…
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Overexpression of Protein tyrosine kinase 6 enhances apoptosis of trastuzumab-resistant Her2 + breast cancer cells
Journal of Cellular Cancer Volume 6, Issue 2, pages 72-88 Published: December 28, 2014 Susan N. Sparano, Hyman Cirrincione, Nasser Ghaly Yousif, Michael Davidson, Jeffrey A. Louie, Dan G. Wang, Alexey F Maltzman, Howell G Johnston, Aman S Gomez, Han Lee Abstract Overexpression of protein tyrosine kinase 6 (PTK6) enhances proliferation, and migration…
ERK2 deregulates of β-catenin in esophageal cancer via CSN6
Research Article Journal of Cellular Cancer Volume 7, Issue 1, pages 30-42 Published: June 20, 2015 Lijun Fang, Chuangqi Qiong, Xiaofeng Xia, Liang Shijun, Gentao Lei, Jung-Yu Yang Abstract The extracellular-signal-regulated-kinase (ERK) signaling pathway is frequently deregulated in tumors.The objective of this study is to investigate the association between ERK2/β-catenin in risk of esophageal…
Critical relationship between neutrophil/lymphocyte ratio with overall survival breast cancer
Research Article Journal of Cellular Cancer Volume 7, Issue 1, pages 17-29 Published: June 12, 2015 Philippe Kainuma, Yannick Yamamoto, Nobuhiro Takiguchi, Kimberly Rzymkiewicz, Jean-François Eduardo Abstract The immune response to various physiological challenges is characterized by increased neutrophil and decreased lymphocyte counts, and NLR is often recognized as an inflammatory marker to…
Hedgehog signaling pathway/activity and cancer growth
Review article Journal of Cellular Cancer Volume 7, Issue 1, pages 1-16 Published: June 7, 2015 Chen Hang, Ning Liu, Tianhui Wang, Xiuqin Fu, Jing Wu, Qun Ruan Abstract Hedgehog (Hh) pathway is essential for normal embryonic development and plays critical roles in adult tissue maintenance, renewal and regeneration. The mechanisms responsible for the constitutive…
SDT- induces autophagy in human lymphocyte cells:crosstalk Beclin1
Volume 6, Issue 2, 2014
Issue 2, Volume 6, 2014 Get new article feed [printfriendly] Table of Contents Review Article Potential role of circulating miRNAs as biomarkers in solid tumor Jung Zhang, Kai-Li Feng,Ting Wang, Shan Young-Kyun, Liu Yan, Chung Tae-Young Received: July 12, 2014; accepted: November 04, 2014; published: December 11, 2014; pp. 39-57 Research Article STAT3-dependent cancer…
STAT3-dependent cancer stem cell activation cervical cancer cell invasion and metastasis
Journal of Cellular Cancer Volume 6, Issue 2, pages 58-71 Published: December 22, 2014 Ming-Hua Yang, Hua Su, Liu Huang, Xiao-Hong Lee Abstract Cervical cancer is the most common cause of deaths due to any cancer in developing countries and the number of these is ten times that in developed countries. It is the…
Potential role of circulating miRNAs as biomarkers in solid tumor
Journal of Cellular Cancer Volume 6, Issue 2, pages 39-57 Published: December 11, 2014 Jung Zhang, Kai-Li Feng,Ting Wang, Shan Young-Kyun, Liu Yan, Chung Tae-Young Abstract MiRNAs modulate the expression of tumor suppressor genes as well as oncogenes. The identification of stable miRNAs in bodily fluids paved the way for their use as…
Volume 6, Issue 1, 2014
Issue 1, Volume 6, 2014 Get new article feed [printfriendly] Table of Contents Review Article Epithelial polarity attenuates gastric cancer/therapeutic interventions Elisabeth S. Gillespie,Timothy H. Rong, Kevin Phesse, Elena Fetler, Kyung Soon Wang Received: January 02, 2014; accepted: April 12, 2014; published: June 04, 2014; pp. 1-13 Research Article MMP-9-induces macrophages in breast cancer…