[post-views] Minoru B.Tada¹, Suzan Kamath, Lindsell E. Norton, Kathleen B. Loomes∗AbstractOvarian cancer is the most lethal gynecologic malignancy. In recent data have shown constitutive upregulation of the Notch1 signaling pathway in many forms of solid and hematological malignancies. However, it remains unclear whether this signaling pathway is activated in ovarian cancer cells. In the present study,…
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Detection of (HPV) using in situ hybridization molecular method in cervical lesions of Iraqi women
Suhad Faisal Hatem Al mugdadi¹, Ban abbas abd- almajeed², Maha Mahamommed Alsayyid³, Zahraa Amer¹, Shahad Ayad¹AbstractHuman papilloma virus is a group of genetically related viruses that commonly infect stratified squamous epithelium. HPVs induce proliferative changes that result in both benign and malignant tumors. HPV causes a mixture of lesions ranging from common warts to cervical…
Cytotoxicity and modulation of synthesized nitrochalcone derivative on rhabdomyosarcoma cell line
http://dx.doi.org/10.18081/jcc/016-06/41-51 Journal of Cellular Cancer Volume 8, Issue 1, pages 41-51 Received March 01, 2016; accepted May 08, 2016; published June 28, 2016 Khalida K. Abbas Al-Kelaby1*, Samer A. Hasan2, Jawad K. Abbas3 Abstract Many efforts have focused on the therapeutic approach of cancer for a long time by studying of cytotoxic activities of plant…
Iraqi national bone marrow registry project
http://dx.doi.org/10.18081/jcc/016-06/34-40 Journal of Cellular Cancer Volume 8, Issue 1, pages 34-40 Received January 21, 2016; accepted May 28, 2016; published June 28, 2016 Shahrazad S Al Jobori1* Abstract Every year, thousands of patients of all ages are in desperate need of bone marrow transplants which may be their only chance to survive. Some patients with…
Real time PCR detection chromosomal translocation in lymphoma by special probe
http://dx.doi.org/10.18081/jcc/016-06/28-33 Journal of Cellular Cancer Volume 8, Issue 1, pages 28-33 Received January 21, 2016; accepted May 28, 2016; published June 28, 2016 Thana Mohammed Juda1*, Seenaa Badr1 Abstract The research of malignancy was mostly reach to facts that the cancer is multifactorial, many risk factors are associated with developing of cancer in normal cell…
Critical role of TGF-β1-induced peritoneal metastasis of ovarian cancer cell through up-regulation of TGF-β type I receptor
http://dx.doi.org/10.18081/jcc/016-06/24-27 Journal of Cellular Cancer Volume 8, Issue 1, pages 24-27 Received January 21, 2016; accepted May 26, 2016; published June 19, 2016 Rory A. Collins, Andres D. Metspalu, Carla M. van El, Andersen S. Mamsen, Charles Y. Dondorp, Lidewij E. Henneman¹* Abstract Ovarian cancer is the most lethal gynecologic malignancy in female due to…
Continuous bevacizumab plus second line chemotherapy beyond progression during or after maintenance bevacizumab
http://dx.doi.org/10.18081/jcc/016-06/12-23 Journal of Cellular Cancer Volume 8, Issue 1, pages 12-23 Received January 28, 2016; accepted May 21, 2016; published June 17, 2016 Haider Y. Shukur1* Abstract Bevacizumab has FDA approval in the first and second line treatment combined with chemotherapy of epithelial ovarian cancer (EOC). Data is lacking on survival outcomes in patients who…
Critical role of BIRC5 amplification in gastric cancer
http://dx.doi.org/10.18081/jcc/016-06/1-15 Journal of Cellular Cancer Volume 8, Issue 1, pages 16-22 Received December 02, 2015; accepted May 20, 2016; published June 13, 2016 Lianghai Zuo1, Jing Wang 2, Feng Xiong1, Jun Hou1* Abstract Baculoviral IAP repeats containing 5 (BIRC5) is negatively encoded proteins regulation and inhibit apoptosis. BIRC5 has been demonstrated to…
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Histological implication of p53 gene expression in oral squamous cell carcinoma
Karima Al Salihi1*, Ihsan Abdullah2, S. L. Ang3 Author Affiliations *Corresponding Author: Electronic address: mrvsa59@gmail.com. ¹College of Veterinary Medicine/Al Muthanna University. ²College of dentistry/Al Muthanna University. ³School of Dental Sciences/ University Science Malaysia/ Malaysia Abstract This study intends to detect the TP53 genetic alterations and mutations in the conserved regions of the TP53…